Actaully something like this happened in "Bishonen Senshi Sailor Moon" Shampoo was trying to cure herself, they didn't know it was a cure for her fought over the water and Ryoga's relative ended up getting splashed. (Said relative was the Teacher from "I, My, Me Starberry Eggs" who had been before crossdressing as a girl.)
A girl Kuno could be interesting the way Yarrow plays it out.
Personally I enjoy giving Mousse a girl curse. It could be interesting if after getting the curse someone (I'd say Kuno just for oddity) accidently beats him and Colonge try to get him to marry the victor.