Here's one:
Challenge: Topcow/Ranma/Sailormoon cross
Ranma becomes the bearer of the Witchblade, the Balance, during the Moxibustion arc.
The Blade only ignores the male form because it can still feel the female form.
Ranma is the host of the Darkness, the agent of Chaos. This might be the reason Nodoka likes to threaten him with seppuku(she doesn't know about it but she hates his father)
The Angelus, the agent of Order, has a new host. Her name is Setsuna Meiou. Destroy chaos! For Crystal Tokyo!
Will Ranma become blood thirsty due to the influence of the Blade and the Darkness?
Points for matchup: Usagi, Ami, Michiru, Hotaru or Haruka.
Points for adding: Tomb Raider, Magdalena. Either can be the originals or a anime character taking the roles.
Point for: making Ranma a combat butler